产品货号：
Z15878
中文名称：
DLL3抗体
英文名称：
Anti-DLL3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DLL3 Antibody |
| 指标别名 | delta like 3 (Drosophila);Delta like protein 3;Delta3;DLL3;Drosophila Delta homolog 3;SCDO1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | DLL3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human DLL3(599-618aa RAGQRQHLLFPYPSSILSVK). |
| 实际分子量 | 65KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DLL3(DELTA-LIKE 3) also known as DELTA,DROSOPHILA,HOMOLOG OF,is a protein which in humans is encoded by the DLL3 gene.This gene encodes a member of the delta protein ligand family.This family functions as Notch ligands that are characterized by a DSL domain,EGF repeats,and a transmembrane domain.Mutation in the mouse delta-like 3 gene(Dll3),which is homologous to the Notch-ligand delta in Drosophila,results in the mouse 'pudgy' phenotype.The human DLL3 gene was identified within a critical interval,mapped in 2 consanguineous Arab-Israeli and Pakistani SCDO1 pedigrees,of 7.8 cM at 19q13.1-q13.3 between D19S570 and D19S908(Bulman et al.,2000).Dunwoodie et al.(1997) presented results suggesting that mouse Dll3 may complement the function of other delta homologs during early pattern formation in the mouse embryo.In humans,the fact that mutations in genes required for oscillation,such as DLL3,result in abnormal segmentation of the vertebral column suggests that the segmentation clock also acts during human embryonic development.This residue is highly conserved in Delta proteins from Drosophila to humans,and the substitution of a charged polar for a nonpolar residue may disrupt the conformation of the DLL3 protein. |
| Uniprot ID | Q9NYJ7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | delta-like 3(Drosophila) |
| 蛋白名全称 | Delta-like protein 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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